News

Proton Technology Developments

Meetings Held to Plan Preliminary Proton CT Experimentation and Testing

Published 5/2023

Paul Mulqueen, CEO of Proton Calibration Technologies and Evgeny Galyaev, CEO of Radiation Detection and Imaging Technologies, met with research team members at a prominent proton therapy center to plan preliminary proton computed tomography testing and experimentation.

Effect of Proposed Episode-Based Payment Models on Advanced Radiotherapy Procedures

Published 11/2020

Researchers at the University of Florida Health Cancer Center concluded in the JCO Oncology Practice article Effect of Proposed Episode-Based Payment Models on Advanced Radiotherapy Procedures that “These data suggest that the RO-APM may have the desired effect of encouraging shorter courses of radiotherapy…”. Due to the high doses involved in hypofractionation, pCT is needed to streamline the clinical processes to ensure that proton Bragg Peaks are delivered safely and effectively.

Physical Uncertainties in the Planning and Delivery of Light Ion Beam Treatments

Published 03/2020

In a AAPM physicist member survey during an oral presentation at the Annual Meeting, 33% of respondents agree that range uncertainty is a primary barrier to further adoption of proton therapy, and an obstacle to the replacement of X-ray therapy by Proton Therapy. And the AAPM Task Group Report 202 – Physical Uncertainties in the Planning and Delivery of Light Ion Beam Treatments – concluded (p. 53) that “It can be seen that there are quite large differences in the determined RLSTPs between the various facilities, indicating that the uncertainty in converting x-ray CT numbers to RLSTPs is significantly larger than indicated by the single facility experiments.”

Fast In Situ Image Reconstruction for Proton Radiography

Published 05/2019

According to the article in the Journal of Radiation Oncology – Fast In Situ Image Reconstruction for Proton Radiography, “Recent studies indicate that tomographic imaging using protons has the potential to provide directly more accurate measurement of RSPs with significantly lower radiation dose than X-rays.”

Catheter-Free Arrhythmia Ablation Using Scanned Proton Beams

Published 10/2020

Journal Article: Proton Therapy will be an indispensable tool for the treatment of cardiac arrythmia. (Mayo Clinic)

Proton Particle Therapy for Cardiac Arrhythmia

Published 05/2020

Mayo Clinic – Human Clinical Trial

First in the World to Treat Human Cardiac Arrhythmia with Proton Beam Therapy

Published 02/2020

CNAO (Pavia, Italy)

Animal Studies of Cardiac Ablation with Proton Beams conducted by Mayo Clinic

Published 04/2019

The Mayo Clinic concluded that “precise target definition and focused energy delivery are paramount in catheter-free ablation.”

In Vivo Range Verification in Proton Therapy

Published 11/2018

Parodi, K., et. al. state regarding proton CT that “very encouraging simulation studies and experimental campaigns with the available prototypes confirm the promise of this modality” in the journal article.

Physical Uncertainties in the Planning and Delivery of Light Ion Beam Treatments

Published 03/2020

The American Association of Medical Physicists (AAPM) Task Group 202, studied x-ray CT-number-to-RLSTP conversion functions for the scanners and protocols at a number of facilities and wrote the report “Physical Uncertainties in the Planning and Delivery of Light Ion Beam Treatments”, concluding that (p.53) “It can be seen that there are quite large differences in the determined RLSTPs between the various facilities, indicating that the uncertainty in converting x-ray CT numbers to RLSTPs is significantly larger than indicated by the single facility experiments.” [This means that proton range uncertainties are “all over the place” — Paul M will do some calculations to quantify the import of these discrepancies.]

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